Photo by Svdmolen via Wikimedia Commons Working with mouse models, research led by the University of Michigan has revealed previously hidden biology of how touch-sensitive hairs create itching sensations. This fundamental discovery opens new avenues for better understanding and potentially addressing human health conditions characterized by persistent itchiness. The work, supported in part by funding from the National Institutes of Health, was published in the journal Neuron.

Pachyonychia congenita. Photo by Ali87090 via Wikimedia Commons Pachyonychia congenita (PC) is a rare genetic disorder caused by mutations in one of five keratin genes. PC produces debilitating plantar calluses and a characteristic thickening of the nails, with no approved treatment options. In a paper in Science Translational Medicine , University of Michigan investigators report that a single stress‑induced keratin, keratin 16 (K16), may help explain why the skin’s response

The newly designed ExoPatch, being removed from a sample of mouse skin, successfully distinguished melanoma from healthy skin in mice. A...

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A study investigating patients diagnosed with, or at risk for, early diffuse systemic sclerosis indicates that standard scleroderma...