Photo courtesy Morguefile.com Researchers have discovered a previously unknown molecular mechanism that contributes to psoriasis development, a discovery that represents a potential biomarker and treatment target. The study, published in Cell Death & Differentiation , shows that the fatty acid-binding protein FABP5 drives ferroptosis, a particular form of cell death, and amplifies inflammatory processes in the skin. Blocking this protein significantly improved the skin changes typically...

Photo by Svdmolen via Wikimedia Commons Researchers at the University of Arizona have identified a previously unknown population of circulating immune cells that play a critical role in fibrosis. The findings, published in Nature Biomedical Engineering , add to the understanding of the healing process and could lead to new strategies for preventing or treating fibrosis. Fibrosis contributes to nearly half of all deaths in developed countries, including conditions such as pulmonary fibrosis,...

Yu-Ying He, PhD. Photo courtesy the University of Chicago In a new study published in Nature Communications , researchers at the University of Chicago have discovered how prolonged exposure to ultraviolet (UV) radiation can trigger inflammation in skin cells by degrading a key protein called YTHDF2. This protein acts as a gatekeeper in preventing normal skin cells from becoming cancerous. The finding reveals that YTHDF2 plays a crucial role in regulating RNA metabolism to maintain cell health...