Immune trajectory shifts in the pre- to post-radiotherapy (RT) tumour microenvironment in cutaneous T-cell lymphoma. Courtesy of Alan Zhou, MD, ‘21 MSc. Researchers have discovered how radiotherapy alters the immune environment within cutaneous T-cell lymphoma (CTCL) tumours, according to findings published in the Journal of the American Academy of Dermatology. The study reveals how radiotherapy not only eliminates cancer cells but also reprograms the surrounding tumour micro

Vashisht Gopal Yennu Nanda, Ph.D. Photo courtesy of The University of Texas MD Anderson Cancer Center Researchers at The University of Texas MD Anderson Cancer Center report that tailoring targeted drug combinations to tumour dependence on BCL2 family proteins may restore treatment responses in patients with advanced melanoma that has progressed on standard BRAF-MEK therapy. These personalized strategies may improve outcomes in this challenging patient population and, in addi

The world’s largest genetics study of ‘moliness’ has uncovered hundreds of genes that play a role in the growth of both moles and melanoma, a discovery that could lead to new ways to prevent and treat the deadliest form of skin cancer. These findings, published in Nature Communications, come from research by a team at QIMR Berghofer Medical Research Institute in Herston, Australia. The team found risk genes linked to biological pathways that could lead to the development of a

Researchers have developed a minimally invasive 'intelligent tattoo' for the early detection of melanoma.

A highly magnified view of melanoma tumours growing in the skin. CD169+ macrophages are shown in green and yellow, forming a biological boundary wall to contain the tumours. Image courtesy Garvan Institute of Medical Research For the first time, researchers have observed macrophages attacking melanoma cells in real time and identified a subpopulation of the immune cells involved in resisting the skin cancer. The findings, published in the Journal of Experimental Medicine, rev

Image by freepik The composition of gut bacteria can predict which melanoma patients will experience cancer recurrence after surgical resection and immunotherapy, but only when matched to patients with similar microbial profiles, according to research published April 17 in Cell. The findings from a 674-patient international clinical trial offer a novel approach to stratifying recurrence risk in high-risk melanoma patients undergoing adjuvant immune checkpoint blockade. Resear

Image courtesy the American Academy of Dermatology Findings from the American Academy of Dermatology’s (AAD) annual Practice Safe Sun Survey, released on May 1, 2026, show that misinformation, social media, and persistent tanning myths are driving many Americans to continue to engage in risky sun behaviours. A statement released by the AAD says the survey results underscore a perception gap between what Americans understand to be safe sun practices and the reality of good hab

Nerves (in green) within a melanoma tumour. Photo by: Dr. David J. Simon Nerve fibres within melanomas can slow tumour growth, according to a study led by Weill Cornell Medicine investigators. The findings help clarify the emerging field of cancer neuroscience and may inform future therapeutic strategies. In the study, published April 29 in Neuron, the researchers used mouse models of melanoma to examine the presence and the effects of peripheral nerves that grow into tumours