Melanoma cells with the cell membrane protein CD44 stained in red and the nucleus in blue. Dil-labelled extracellular vesicles taken up by cancer cells are shown in green. Image by Kaisa Mäki-Mantila. Pro-inflammatory macrophages may do more than mark an inflamed tumour microenvironment; they may help drive melanoma toward a more invasive phenotype, according to new data from the University of Eastern Finland. The findings, published in Cell Communication and Signaling , posi

Photo by Amanda Mills, USCDCP, via Pixnio A long-running Queensland, Australia, study has found children are developing significantly fewer moles than their peers were 25 years ago, with predictions of a major reduction in future melanoma risk. The Brisbane Twin Nevus Study, published in the  British Journal of Dermatology , tracked the development of moles in twins and their siblings who turned 12 each year from 1992 to 2016. There were a total of 3,957 participants living i

Researchers at Oregon State University have developed a new nanoparticle to allow the removal of melanoma tumours using low-power laser light.

Dermatofibrosarcoma protuberans (DFSP) of the face. Photo by Tontonflingueur via Wikimedia Commons Dermatofibrosarcoma protuberans (DFSP) rarely affects the head and face—but when it does, new research suggests the cheek is the prime location. In what is described as the largest clinical cohort of facial DFSP to date, investigators at a single Chinese institution have mapped the complex distribution of the tumour across facial subunits, uncovering distinct anatomic and biolog

Tanning bed use is tied to almost a threefold increase in melanoma risk, and findings from new research show these devices cause melanoma-linked DNA damage across nearly the entire skin surface. The findings were reported in a study published in Science Advances  led by Northwestern Medicine in Chicago and the University of California, San Francisco. This new study “irrefutably” challenges claims from the tanning industry that tanning beds are no more harmful than sunlight by

A new analysis in JAMA Dermatology  reports that nicotinamide, a form of vitamin B3, was associated with a meaningful reduction in incident skin cancers among U.S. veterans with a prior history of the disease. The findings point to an inexpensive, orally administered chemopreventive option that could help clinicians manage an especially high‑risk population. The study drew on data from more than 12,000 veterans followed over 25 years who had previously received nicotinamide a

Photo by curretett on Freeimages.com Young adults who use tanning beds may be aging their skin cells at a molecular level much faster than their chronological age suggests, according to a new study from the University of California, San Francisco (UCSF) and Northwestern University. The research, published December 12 in Science Advances , reports that tanning bed users in their 30s and 40s harbour more mutations in their skin cells than nonusers who were in their 70s or 80s.

A registry study from Lund University in Sweden shows a possible increased risk of basal cell carcinoma with certain blood pressure medications. Because the risk increase is relatively low, 9% or lower, the researchers do not recommend treatment discontinuation. Instead, physicians should inform their patients that extra sun protection may be needed. The study’s lead author, Johan Kappelin, PhD, is a senior consultant at the dermatology clinic in Landskrona, Sweden. “Basal c