Botulinum toxin may offer a practical new option for patients with painful, treatment‑resistant ischemic lesions of the fingers, according to a systematic review and individual‑patient meta‑analysis published in JAMA Dermatology  by investigators at the McGill University Health Centre (MUHC) in Montreal. Researchers at the Research Institute of the MUHC report that injections of botulinum toxin were associated with complete healing of digital lesions in more than 85% of 119 patients with...

Photo by Benis Arapovic via Vecteezy Researchers in Arkansas are developing experimental surgical sutures that slowly release anti-inflammatory drugs at the wound site, aiming to curb local inflammation, reduce scarring, and potentially improve outcomes of delicate procedures. Working in the laboratory of chemist Sharon K. Hamilton, PhD, at Ouachita Baptist University, undergraduate researcher Mieya Kirby has focused on electrospun polymers, which can be drawn under high voltage into...

MFSD2A is required for the uptake of LPCs containing linoleic acid (LPC18:2) from the blood for normal development of the epidermis. The absence of MFSD2A leads to increased skin inflammation and thickening of the epidermis. Photo by: Bernice Wong Researchers at Duke-NUS Medical School in Singapore have pinpointed a lipid transporter that enables epidermal cells to import key fatty acids from the bloodstream, a mechanism they say is critical for preserving skin barrier integrity in health and...