Photo by James Heilman, MD via Wikimedia Commons New research shows that adults with atopic dermatitis (AD), particularly those with childhood onset, report significantly greater limitations in their educational and professional choices. Investigators found that up to 38% of childhood-onset patients reported career restrictions and more than 36% reporting constrained study choices, compared to individuals whose disease began in adulthood. The authors say their findings, publi

Staphylococcus aureus. Photo by Janice Haney Carr, provided by CDC/ Matthew J. Arduino, DRPH, via Wikimedia Commons New findings suggest that commensal bacteria on the skin release molecules that inhibit the skin’s production of pro-inflammatory interleukin (IL)-33, potentially preventing atopic dermatitis (AD) flares. Published in Nature Communications, the findings come from research conducted at the University of Manchester and Tokyo University of Agriculture and Technolog

Image by evening_tao on Freepik A study in Japanese children has found that early-life exposure to residential "greenness" was associated with a decreased risk of atopic dermatitis. The study authors describe greenness as vegetation such as trees, grass, and other plants, whether in planned areas such as parks and street trees or in unplanned natural regions. Published in Pediatric Allergy and Immunology, the study evaluated data from 14,932 children in the Tohoku Medical Meg

Photo by Gzzz via Wikimedia Commons For the first time, the American Academy of Dermatology (AAD) has published guidelines for the prevention and management of atopic dermatitis (AD) in pediatric patients. A press release from the Academy notes that while pediatric and adult AD share similarities, the new guidelines recognize the unique safety, dosing, and patient-caregiver-clinician interactions of individuals under the age of 18. “Eczema is extremely common in children, th

Child with Atopic Dermatitis Photo by Eisfelder via Wikimedia Commons A new study shows that treatment with dupilumab significantly restores skin barrier function and reduces inflammation in children aged 6 to 11 years with moderate-to-severe atopic dermatitis (AD). Researchers found improvements not only in visible AD lesions but also in clinically unaffected skin, highlighting the systemic nature of the disease. The findings were published in Annals of Allergy, Asthma & Imm

TRPV4, an ion channel, is found in neurons classically associated with touch, called Aβ low-threshold mechanoreceptors. New research indicates that TRPV4 can generate itch, but it also helps trigger a negative feedback signal, a neural message that tells the spinal cord and brain that scratching has been sufficient. Image Courtesy of Roberta Gualdani Researchers have discovered that the ion channel TRPV4 plays a critical role in regulating the body's built-in "stop-scratching

Photo by AfroBrazilian via Wikimedia Commons A new study, published in JMIR Dermatology , has identified a disconnect between how patients with atopic dermatitis (AD) experience climate-related triggers and how often these concerns are addressed in clinical care. The researchers say their findings underscore a need for tools and strategies to support climate-health conversations in dermatology. For the study, investigators initially selected 2,164 English-speaking adults with

Excess rate (segment width) as the proportion of the sum of all excess rates from crude results from (a) the any-age cohort (i.e., exposed individuals met the eczema definition at any age), (b) the < 18 cohort (exposed individuals met the eczema definition before their 18 th birthday). Each outcome is defined as a 3-character ICD-10 code and its descendants. Labels and increased opacity of segments are shown for outcomes with the largest individual excess rate estimates that