TRPV4, an ion channel, is found in neurons classically associated with touch, called Aβ low-threshold mechanoreceptors. New research indicates that TRPV4 can generate itch, but it also helps trigger a negative feedback signal, a neural message that tells the spinal cord and brain that scratching has been sufficient. Image Courtesy of Roberta Gualdani Researchers have discovered that the ion channel TRPV4 plays a critical role in regulating the body's built-in "stop-scratching

Photo by AfroBrazilian via Wikimedia Commons A new study, published in JMIR Dermatology , has identified a disconnect between how patients with atopic dermatitis (AD) experience climate-related triggers and how often these concerns are addressed in clinical care. The researchers say their findings underscore a need for tools and strategies to support climate-health conversations in dermatology. For the study, investigators initially selected 2,164 English-speaking adults with

Excess rate (segment width) as the proportion of the sum of all excess rates from crude results from (a) the any-age cohort (i.e., exposed individuals met the eczema definition at any age), (b) the < 18 cohort (exposed individuals met the eczema definition before their 18 th birthday). Each outcome is defined as a 3-character ICD-10 code and its descendants. Labels and increased opacity of segments are shown for outcomes with the largest individual excess rate estimates that

Pustular psoriasis. Photo by Roland Tanglao via Wikimedia Commons Cutaneous paradoxical reactions to biologic therapies for psoriasis and atopic dermatitis are emerging as an important, if unpredictable, complication of these otherwise highly targeted treatments, according to Dr. Jeffrey Marcus Cohen . In a report in the Dec. 2025 issue of The Chronicle of Skin & Allergy , Dr. Cohen noted monoclonal antibodies have transformed care by addressing the underlying immunology of c

Photo by Care_SMC via Flickr The timing, duration, and severity of eczema in early life may significantly influence whether children outgrow food allergies, according to findings presented at the American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting in Orlando, Fla. “Food allergy and eczema often appear together in childhood, but scientists don’t fully understand how one condition affects the other,” said Nicole Koulov, in a press release . She

Atopic dermatitis. Photo by AfroBrazilian via Wikimedia Commons Two new studies presented at the 2025 Annual Scientific Meeting of the American College of Allergy, Asthma and Immunology (ACAAI) show that people with eczema or allergic conditions may face more problems after certain types of surgery. The research suggests that the inflammation and immune system changes that come with these conditions can make it harder for the body to heal and may increase the risk of infectio

Image by Standl M. et al. CC:BY Findings from a new study suggest early-life exposure to domestic dogs may modify the effect of one...

Photo by Dwxn via Wikimedia Commons New research reveals that patients with moderate-to-severe atopic dermatitis (AD) who did not...