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Topical 4-AP gel promising for burn wound closure
Second-degree burn wound after two days of healing. Phot by Cjr80 via Wikimedia Commons A topical gel formulation of 4-aminopyridine (4-AP) for the treatment of burn wounds has achieved near-complete closure within 21 days in animal models. The findings were published in the journal Biomaterials. Researchers at the Terasaki Institute for Biomedical Innovation and the University of Arizona College of Medicine have developed the new formulation. The medication is best known und
John Evans
19 hours ago2 min read


Topical LSD1 inhibitor shows promise for cSSC Tx
Squamous cell carcinoma in situ. Photo by Klaus D. Peter via Wikimedia Commons Findings from a preclinical study show a topical cream that blocks the immune-suppressing enzyme LSD1 suppressed tumour growth in two models of cutaneous squamous cell carcinoma (cSCC). The study, published in the Journal of Clinical Investigation , describes how the cream, developed by researchers at the Perelman School of Medicine at the University of Pennsylvania in Philadelphia, prevents LSD1
John Evans
Mar 202 min read


Topical Tx reduces cutaneous neuropathy from cancer chemotherapy
Image by freepik Researchers have developed a topical cream that relieves some cutaneous side effects of chemotherapy with taxanes or...
John Evans
Oct 10, 20252 min read


Twelve-month results of topical clascoterone for acne promising
Findings from an open-label, long-term extension study show topical clascoterone cream 1% maintained a favourable safety and efficacy...
John Evans
Sep 22, 20231 min read


Studies examine optimal topical, systemic Txs for AD
Two reviews from researchers at McMaster University in Hamilton have identified the most effective topical and systemic treatments for...
Allan Ryan
Sep 18, 20232 min read


Topical therapy study results promising for ichthyosis
A new study from Yale University School of Medicine provides additional evidence that an investigational topical can be beneficial for...
Allan Ryan
Apr 17, 20232 min read


AD prophylaxis in high-risk infants: Emollient emulsions may produce best outcomes
An assessment of various types of skin moisturizers suggests an emollient emulsion may be the most effective option to help prevent...
Allan Ryan
Nov 28, 20221 min read


Study shows high percentage of ‘natural’ skin care products contain allergens
Nearly 90% of 1,651 so-called ‘natural’ personal care products contain at least one known allergen, according to a new study from...
Allan Ryan
Nov 21, 20221 min read
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