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Hair follicles harbour sentinel cells for immune surveillance
Photo by OpenStax College via Wikimedia Commons Researchers at the University of California, Riverside School of Medicine have identified previously unrecognized immune surveillance structures within hair follicles that may fundamentally change the concept of cutaneous barrier defence. The murine study, published in Frontiers in Cell and Developmental Biology, reveals M cell-like sentinel cells in hair follicle epithelium that appear to monitor environmental microbial exposur
Allan Ryan
1 hour ago2 min read


Exposure to residential greenness may reduce AD risk
Image by evening_tao on Freepik A study in Japanese children has found that early-life exposure to residential "greenness" was associated with a decreased risk of atopic dermatitis. The study authors describe greenness as vegetation such as trees, grass, and other plants, whether in planned areas such as parks and street trees or in unplanned natural regions. Published in Pediatric Allergy and Immunology, the study evaluated data from 14,932 children in the Tohoku Medical Meg
John Evans
3 days ago2 min read


VIDEO: Melanoma immune cell composition may predict benefit from combination immunotherapy
The tumour immune cell environment may determine whether or not a melanoma patient will respond to combination immunotherapy
Jeremy Visser
6 days ago1 min read


Mental health, dermatology-related quality of life, and the role of probiotics
Photo by Ketut Subiyanto via Pexels Mental health symptoms and skin disease appear to be connected for many adults, especially for women, according to a new Brazilian study published in the Journal of Dermatologic Science and Cosmetic Technology . The researchers investigated the skin–brain axis and looked at the presumed benefits of probiotics. Their findings suggest that common psychiatric symptoms, rather than diet-related microbial factors, may be the primary drivers o
Allan Ryan
Apr 202 min read


Bee propolis extract shows promise in scar prevention
Pieces of propolis. Photo by Goldmull via Wikimedia Commons A natural compound made by Australian bees to seal their hives may help stop scarring in human skin after surgery, injury, and burns, according to researchers from the University of the Sunshine Coast in Queensland, Australia. In a press release from the university, the scientists say the laboratory finding has “immense potential” for future applications in people with scarring of any severity. The compound was foun
John Evans
Apr 172 min read


VIDEO: Sun safety campaigns may be linked to plateauing melanoma cases in Australia
According to a recent study, a plateauing of second primary invasive cutaneous melanoma cases in Australia may be linked to the success of sun safety campaigns.
Jeremy Visser
Apr 151 min read


Genetic disease offers new clues to skin inflammation
Pachyonychia congenita. Photo by Ali87090 via Wikimedia Commons Pachyonychia congenita (PC) is a rare genetic disorder caused by mutations in one of five keratin genes. PC produces debilitating plantar calluses and a characteristic thickening of the nails, with no approved treatment options. In a paper in Science Translational Medicine , University of Michigan investigators report that a single stress‑induced keratin, keratin 16 (K16), may help explain why the skin’s response
Allan Ryan
Apr 132 min read


AAD releases pediatric AD guidelines
Photo by Gzzz via Wikimedia Commons For the first time, the American Academy of Dermatology (AAD) has published guidelines for the prevention and management of atopic dermatitis (AD) in pediatric patients. A press release from the Academy notes that while pediatric and adult AD share similarities, the new guidelines recognize the unique safety, dosing, and patient-caregiver-clinician interactions of individuals under the age of 18. “Eczema is extremely common in children, th
John Evans
Apr 103 min read
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