Researchers identify biologics for psoriasis that have better drug survival in bio-naive or bio-experienced patients.

Pustular psoriasis. Photo by Roland Tanglao via Wikimedia Commons Cutaneous paradoxical reactions to biologic therapies for psoriasis and atopic dermatitis are emerging as an important, if unpredictable, complication of these otherwise highly targeted treatments, according to Dr. Jeffrey Marcus Cohen . In a report in the Dec. 2025 issue of The Chronicle of Skin & Allergy , Dr. Cohen noted monoclonal antibodies have transformed care by addressing the underlying immunology of c

Tanning bed use is tied to almost a threefold increase in melanoma risk, and findings from new research show these devices cause melanoma-linked DNA damage across nearly the entire skin surface. The findings were reported in a study published in Science Advances  led by Northwestern Medicine in Chicago and the University of California, San Francisco. This new study “irrefutably” challenges claims from the tanning industry that tanning beds are no more harmful than sunlight by

Patients with chronic skin diseases have higher rates of addictive behaviours.

A new analysis in JAMA Dermatology  reports that nicotinamide, a form of vitamin B3, was associated with a meaningful reduction in incident skin cancers among U.S. veterans with a prior history of the disease. The findings point to an inexpensive, orally administered chemopreventive option that could help clinicians manage an especially high‑risk population. The study drew on data from more than 12,000 veterans followed over 25 years who had previously received nicotinamide a

Tyrosinase (Tyr) catalyzes hydroquinone (HQ) oxidation via two main pathways. The HBQ pathway directly oxidizes HQ to 2-hydroxy-1,4-benzoquinone (HBQ), which dimerizes and forms hydroquinone-eumelanin (HQ-EM). The BQ pathway involves dopaquinone (DQ)-mediated redox exchange producing p-benzoquinone (BQ), which reacts with cysteine (Cys) to form 2-S-cysteinylhydroquinone (Cys-HQ) and further oxidizes to hydroquinone-pheomelanin (HQ-PM). These pathways illustrate the enzymatic

46.3% of female patients with psoriasis have been exposed to at least one type of intimate partner violence.

Photo by curretett on Freeimages.com Young adults who use tanning beds may be aging their skin cells at a molecular level much faster than their chronological age suggests, according to a new study from the University of California, San Francisco (UCSF) and Northwestern University. The research, published December 12 in Science Advances , reports that tanning bed users in their 30s and 40s harbour more mutations in their skin cells than nonusers who were in their 70s or 80s.