Photo courtesy Morguefile.com Researchers have discovered a previously unknown molecular mechanism that contributes to psoriasis development, a discovery that represents a potential biomarker and treatment target. The study, published in Cell Death & Differentiation , shows that the fatty acid-binding protein FABP5 drives ferroptosis, a particular form of cell death, and amplifies inflammatory processes in the skin. Blocking this protein significantly improved the skin change

Probiotics as adjunctive therapy for acen vulgaris do not result in a statistically significant improvement in disease severity.

Illustration courtesy Juliet M. Pullar et al. J Invest Dermatol 2025 Oct. 29:S0022-202X(25)03509-2 A new study from the University of Otago in Christchurch, New Zealand, has found that dietary vitamin C intake directly enhances collagen production and skin renewal, offering clinical confirmation that nutrition may play a central role in skin physiology. Published in the Journal of Investigative Dermatology , the investigation established a strong, dose-responsive relationship

A registry study from Lund University in Sweden shows a possible increased risk of basal cell carcinoma with certain blood pressure medications. Because the risk increase is relatively low, 9% or lower, the researchers do not recommend treatment discontinuation. Instead, physicians should inform their patients that extra sun protection may be needed. The study’s lead author, Johan Kappelin, PhD, is a senior consultant at the dermatology clinic in Landskrona, Sweden. “Basal c

Patients with severe AD have higher rates of venous thromboembolism than those with moderate AD or without AD.

Early stage TEN. Photo by Jay2Base via Wikimedia Commons Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) may be rare, but for many patients the crisis does not end at hospital discharge. A new qualitative study published in JAMA Dermatology  describes years of persistent physical, psychological, and social fallout—and a striking absence of structured post-discharge care. Investigators at Vanderbilt University Medical Center’s Center for Drug Safety and Imm

Photo by Svdmolen via Wikimedia Commons Researchers at the University of Arizona have identified a previously unknown population of circulating immune cells that play a critical role in fibrosis. The findings, published in Nature Biomedical Engineering , add to the understanding of the healing process and could lead to new strategies for preventing or treating fibrosis. Fibrosis contributes to nearly half of all deaths in developed countries, including conditions such as pulm

Patients with AD have a higher risk of non-melanoma skin cancers.