Early stage TEN. Photo by Jay2Base via Wikimedia Commons Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) may be rare, but for many patients the crisis does not end at hospital discharge. A new qualitative study published in JAMA Dermatology  describes years of persistent physical, psychological, and social fallout—and a striking absence of structured post-discharge care. Investigators at Vanderbilt University Medical Center’s Center for Drug Safety and Imm

The FPR1-inhibitory activity of the candidate compounds was evaluated using an in vitro SJS/TEN assay. Cell death inhibition was assessed by live/dead staining following treatment with various concentrations of each compound. Among the seven candidates, CDCA exhibited a specific and potent inhibitory effect on cell death, even at low concentrations. Image modified from Kimura H et al., Nat Commun . 2025. A Japanese research group has identified a promising therapeutic candida

Researchers have successfully treated seven patients experiencing toxic epidermal necrolysis (TEN) using JAK inhibitors. All seven...