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Guselkumab offers long-term safety in all skin types
All patients self-identified as non-White and nearly 69% of treated subjects had objectively measured Fitzpatrick skin types IV through VI The IL-23 inhibitor guselkumab demonstrated efficacy out to 100 weeks in the treatment of psoriasis across a spectrum of skin types, according to poster research presented at the 2026 annual meeting of the American Academy of Dermatology (AAD) in Denver. A full report will be published in the June 2026 issue of The Chronicle of Skin & Alle
Allan Ryan
Jun 83 min read


Psoriasis and the Mediterranean diet
Photo by G.steph.rocket via Wikimedia Commons Study shows positive effects of diet on normal-weight patients with psoriasis A healthy diet is widely considered to play a role in improving psoriasis symptoms, supporting the anti-inflammatory benefits of weight loss in overweight or obese psoriasis patients, but there are benefits independent of weight loss seen in patients of all body weights. That’s according to Dr. Javier Perez-Bootelloof, Hospital Universitario Ramón y Caja
Allan Ryan
Jun 13 min read


Neural mechanism signals the body to stop scratching
TRPV4, an ion channel, is found in neurons classically associated with touch, called Aβ low-threshold mechanoreceptors. New research indicates that TRPV4 can generate itch, but it also helps trigger a negative feedback signal, a neural message that tells the spinal cord and brain that scratching has been sufficient. Image Courtesy of Roberta Gualdani Researchers have discovered that the ion channel TRPV4 plays a critical role in regulating the body's built-in "stop-scratching
Allan Ryan
Feb 232 min read


Advanced treatments for psoriasis, AD may produce paradoxical reactions
Pustular psoriasis. Photo by Roland Tanglao via Wikimedia Commons Cutaneous paradoxical reactions to biologic therapies for psoriasis and atopic dermatitis are emerging as an important, if unpredictable, complication of these otherwise highly targeted treatments, according to Dr. Jeffrey Marcus Cohen . In a report in the Dec. 2025 issue of The Chronicle of Skin & Allergy , Dr. Cohen noted monoclonal antibodies have transformed care by addressing the underlying immunology of c
Allan Ryan
Jan 192 min read


Early family life stress raises psoriasis risk
New longitudinal research reveals that severe stress caused by changes in family structure—such as divorce or separation—experienced during the first year of life may triple the risk of developing psoriasis later in life. The results of the study, published in the Journal of Investigative Dermatology , emphasize the need to protect young children from stressful life factors that threaten their security and emotional well-being. According to a press release , this is the first
John Evans
Oct 24, 20252 min read


Nail psoriasis: N-NAIL shows higher diagnostic accuracy in study
Photo by: JVO27 via Wikimedia Commons Findings from a study comparing the Nijmegen-Nail Psoriasis Activity Index Tool (N-NAIL) and Nail...
John Evans
Sep 5, 20251 min read


SSAT inhibition a possible new target for psoriasis Tx
Credit: Immunity (2025) Findings from a new study published in the journal Immunity suggest it may be possible to restore the function...
John Evans
Mar 7, 20252 min read


Protein has key role in psoriasis inflammation
Photo by: Haley Otman via Wikimedia Commons Researchers at Case Western Reserve University School of Medicine in Cleveland have...
Allan Ryan
Feb 3, 20252 min read
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