TRPV4, an ion channel, is found in neurons classically associated with touch, called Aβ low-threshold mechanoreceptors. New research indicates that TRPV4 can generate itch, but it also helps trigger a negative feedback signal, a neural message that tells the spinal cord and brain that scratching has been sufficient. Image Courtesy of Roberta Gualdani Researchers have discovered that the ion channel TRPV4 plays a critical role in regulating the body's built-in "stop-scratching

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A new study published in the British Journal of Dermatology has revealed that people with chronic pruritus are twice as likely to...

New research shows that the Janus kinase (JAK) inhibitor abrocitinib, approved in Canada for the treatment of moderate-to-severe atopic...

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While there is only limited evidence that herbal remedies have a clinical effect on chronic pruritus, it does appear that turmeric,...

Findings from a case study from Johns Hopkins University School of Medicine suggest that medical cannabis may be an effective treatment...

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