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mRNA vaccine/pembrolizumab combo reduces post-surgery melanoma recurrence, death risk
In a new study, adding an individualized mRNA-based vaccine to post-surgery pembrolizumab immunotherapy for high-risk melanoma reduced the risk of melanoma recurrence or death by 42% compared with pembrolizumab alone. The findings were announced in a presentation at the ESMO (European Society for Medical Oncology) Congress 2026 in Madrid. According to a press release from the Melanoma Institute Australia, positive results in melanoma suggest this personalized approach may ena
John Evans
2 days ago2 min read


Immunotherapy effective for rare melanoma, study finds
Dr. Antoni Ribas, senior author of the study and director of the UCLA Health Jonsson Comprehensive Cancer Center’s Tumour Immunology...
Derm City
Aug 18, 20252 min read
Investigational melanoma vaccine receives breakthrough designation from U.S. FDA
Data from a Phase 2b study indicates that an investigational personalized mRNA cancer vaccine known as mRNA-4157/V940, in combination...
Allan Ryan
Feb 27, 20232 min read


Pembrolizumab lowered risk of stage IIb/c melanoma recurrence
The immunotherapy medication pembrolizumab, approved for the treatment of stage III and IV melanoma, has been shown to reduce...
John Evans
Sep 24, 20212 min read


VIDEO: Fecal microbiota transplant may help melanoma patients respond to immunotherapy
A proof-of-principle study has found that fecal transplants may help advanced melanoma patients respond to immunotherapy better.
Cory Perla
Feb 10, 20211 min read
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