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Pro-inflammatory M1 macrophages induce an inflammatory, invasive phenotype in melanoma cells
Melanoma cells with the cell membrane protein CD44 stained in red and the nucleus in blue. Dil-labelled extracellular vesicles taken up by cancer cells are shown in green. Image by Kaisa Mäki-Mantila. Pro-inflammatory macrophages may do more than mark an inflamed tumour microenvironment; they may help drive melanoma toward a more invasive phenotype, according to new data from the University of Eastern Finland. The findings, published in Cell Communication and Signaling , posi
Allan Ryan
11 hours ago2 min read


Key mechanism of bone destruction in melanoma bone destruction identified
Photo by: MAKY.OREL via Wikimedia Commons Researchers have identified ferroptosis as the primary mechanism driving osteocyte death in...
Derm City
Jan 27, 20252 min read


Potential Tx to prevent melanoma metastasis identified
New findings from a research team led by investigators from the Medical University of Vienna, Austria, suggest that kinase inhibitors may...
John Evans
Nov 24, 20232 min read


Identified: Signalling cascade involved in melanoma amoeboid cell aggression
Researchers have found new insight into the mechanisms by which a highly invasive subset of melanoma cells on the periphery of...
John Evans
Oct 23, 20202 min read
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