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AI-guided CRISPR study identifies potential topical psoriasis treatments
An AI-guided network analysis of genomic data (left) highlights two protein targets, including the oxytocin receptor, identified through Biohub’s CRISPR screen in primary human skin cells (right). Image by Zhao, C., Shih, M., Ahmed, S. et al. Nat Commun (2026). Researchers have combined genome-wide CRISPR screening with artificial intelligence to identify two unexpected therapeutic targets for psoriasis, opening a possible path toward topical treatments that avoid systemic im
Allan Ryan
Aug 102 min read


Secukinumab shows positive effects in HS at 52 weeks
Patients with moderate to severe hidradenitis suppurativa (HS) treated with secukinumab demonstrate sustained efficacy and symptom...
Allan Ryan
Feb 6, 20232 min read


Psoriatic inflammation improves with bile acids
Some bile acids may help to improve or prevent the skin inflammation associated with psoriasis, according to the results of a study...
John Evans
Feb 14, 20222 min read


Two-year data indicates bimekizumab maintains high levels of psoriatic skin clearance
Study results indicate that maintenance doses of bimekizumab (320 mg) every four or eight weeks can maintain high levels of skin...
John Evans
Aug 9, 20211 min read
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