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Topical LSD1 inhibitor shows promise for cSSC Tx
Squamous cell carcinoma in situ. Photo by Klaus D. Peter via Wikimedia Commons Findings from a preclinical study show a topical cream that blocks the immune-suppressing enzyme LSD1 suppressed tumour growth in two models of cutaneous squamous cell carcinoma (cSCC). The study, published in the Journal of Clinical Investigation , describes how the cream, developed by researchers at the Perelman School of Medicine at the University of Pennsylvania in Philadelphia, prevents LSD1
John Evans
Mar 202 min read


IL-17 may play key role in skin aging
The results of new Spanish research indicate that the pro-inflammatory cytokine IL-17 is central to skin aging and could potentially be...
Allan Ryan
Jul 24, 20232 min read


CD4+ T cells in moles may have a role in melanoma Tx
Researchers have found that common moles on the skin contain a quantity of CD4+ T cells that could in principle be activated as a...
John Evans
Jun 25, 20212 min read
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