A new analysis in JAMA Dermatology  reports that nicotinamide, a form of vitamin B3, was associated with a meaningful reduction in incident skin cancers among U.S. veterans with a prior history of the disease. The findings point to an inexpensive, orally administered chemopreventive option that could help clinicians manage an especially high‑risk population. The study drew on data from more than 12,000 veterans followed over 25 years who had previously received nicotinamide a

Yu-Ying He, PhD. Photo courtesy the University of Chicago In a new study published in Nature Communications , researchers at the University of Chicago have discovered how prolonged exposure to ultraviolet (UV) radiation can trigger inflammation in skin cells by degrading a key protein called YTHDF2. This protein acts as a gatekeeper in preventing normal skin cells from becoming cancerous. The finding reveals that YTHDF2 plays a crucial role in regulating RNA metabolism to mai