An AI-guided network analysis of genomic data (left) highlights two protein targets, including the oxytocin receptor, identified through Biohub’s CRISPR screen in primary human skin cells (right). Image by Zhao, C., Shih, M., Ahmed, S. et al. Nat Commun (2026). Researchers have combined genome-wide CRISPR screening with artificial intelligence to identify two unexpected therapeutic targets for psoriasis, opening a possible path toward topical treatments that avoid systemic im