Ampyrone increases pigmentation in a human 3D epidermal model, The top row shows visible epidermal darkening after treatment every other day with ampyrone for 21 days as compared to negative control. The bottom row shows magnification of epidermal cells revealing increased melanin synthesis in the ampyrone treated melanocytes as compared to negative control. Positive control is alpha-melanocyte stimulating hormone (αMSH) plus beta-fibroblast growth factor (βFGF). Photo by Dr.

Nerves (in green) within a melanoma tumour. Photo by: Dr. David J. Simon Nerve fibres within melanomas can slow tumour growth, according to a study led by Weill Cornell Medicine investigators. The findings help clarify the emerging field of cancer neuroscience and may inform future therapeutic strategies. In the study, published April 29 in Neuron, the researchers used mouse models of melanoma to examine the presence and the effects of peripheral nerves that grow into tumours

Dr. Niroshana Anandasabapathy. Photo courtesy Weill Cornell Medicine Researchers have discovered that the immune-regulating molecule...