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Pro-inflammatory M1 macrophages induce an inflammatory, invasive phenotype in melanoma cells
Melanoma cells with the cell membrane protein CD44 stained in red and the nucleus in blue. Dil-labelled extracellular vesicles taken up by cancer cells are shown in green. Image by Kaisa Mäki-Mantila. Pro-inflammatory macrophages may do more than mark an inflamed tumour microenvironment; they may help drive melanoma toward a more invasive phenotype, according to new data from the University of Eastern Finland. The findings, published in Cell Communication and Signaling , posi
Allan Ryan
Mar 92 min read


Advanced treatments for psoriasis, AD may produce paradoxical reactions
Pustular psoriasis. Photo by Roland Tanglao via Wikimedia Commons Cutaneous paradoxical reactions to biologic therapies for psoriasis and atopic dermatitis are emerging as an important, if unpredictable, complication of these otherwise highly targeted treatments, according to Dr. Jeffrey Marcus Cohen . In a report in the Dec. 2025 issue of The Chronicle of Skin & Allergy , Dr. Cohen noted monoclonal antibodies have transformed care by addressing the underlying immunology of c
Allan Ryan
Jan 192 min read


Yale study links psoriasis, OCD
Researchers at Yale School of Medicine have identified a significant association between psoriasis and obsessive-compulsive disorder...
Allan Ryan
Aug 12, 20242 min read
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