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Jul 20, 2016
2 min

High temperatures linked with increased risk of skin cancer

While exposure to ultra-violet (UV) light has been established as a cause of skin cancer, new research has found that temperature may also play a critical role. Researchers from The Edith Cowan University’s Melanoma Research Group in Perth, Australia, exposed two samples of human skin cells to UV light, keeping one sample at 37°C and the other at 39°C. The study was published in the journal Bio Med Central Dermatology (May 26, 2016). When they analyzed the skin cells they fou

by Lynn Bradshaw, Senior Editor

Jun 23, 2016
1 min

CDA releases winners of 2016 Public Education Awards

Recipients of the 2016 Public Education Awards Program have been unveiled today by the Canadian Dermatology Association (CDA). The Public Education Awards Program is designed to publicly recognize the role played by the media, not-for-profit health organizations and industry in furthering the understanding of dermatology issues and encouraging healthy behaviour in the medical, surgical and cosmetic care of skin, hair and nails. "This year's winners showed tremendous initiativ

John Evans

May 6, 2016
2 min

Fighting the stigma of birthmarks

Image courtesy of Jessica Passecker Photography, via Flawless Affect Inspired by a childhood marked by scrutiny and bullying due to the prominent port-wine stain birthmark on her face, Los Angeles-based model and actress Paige Billiot has launched a collaborative art project to try and reduce the stigma associated with birthmarks and other visible differences. Called Flawless Affect, the project “provides a creative outlet that showcases participants’ flaws in a new and beaut

Derm City

May 2, 2016
2 min

Pigment cells alter melanin production in the presence of estrogen, progesterone

Researchers from the Perelman School of Medicine at the University of Pennsylvania in Philadelphia have found that estrogen and progesterone reciprocally regulate melanin synthesis in epidermal melanocytes, according to a paper published in eLife (Apr. 26, 2016; 10.7544/eLife.15104). The findings potentially explain skin colour changes observed in pregnant women and may open avenues of research into methods of altering skin colour without exposure to ultraviolet (UV) light or

Good results from trial of immunotherapy for Merkel cell carcinoma

Derm City

Apr 22, 2016
2 min

Good results from trial of immunotherapy for Merkel cell carcinoma

Multispectral immunofluorescence showing the interface between Merkel cell tumor cells (orange) and host immune cells (yellow marks CD8+ lymphocytes, red marks CD68+ macrophages). Cell-surface PD-L1 expression (green) is observed on macrophages, lymphocytes and tumor cells, adjacent to PD-1 expression (white) on lymphocytes. Courtesy of Janis Taube, Johns Hopkins. Results from a clinical trial of the immunotherapy drug pembrolizumab as a treatment for Merkel cell carcinoma sh

Derm City

Apr 8, 2016
2 min

Different melanoma treatment approach needed in older vs. younger patients

Age-related changes in how fibroblasts behave appear to both contribute to angiogenesis and metastasis of skin cancer tumours, and to resistance to certain types of targeted therapy, suggesting that patient age needs to be taken into account when developing a program of melanoma therapy, researchers report in a paper published online ahead of print in Nature (Apr. 4, 2016). The authors report that older fibroblasts secrete a protein known as sFRP2, an antagonist to the wnt si

EADV report finds outdoor workers have two-fold increased risk of developing NMSC

Derm City

Mar 30, 2016
2 min

EADV report finds outdoor workers have two-fold increased risk of developing NMSC

Pixabay Almost 14.5 million workers in Europe spend at least 75% of their working time under the sun, and a new report showed that this significant proportion of Europe’s workforce is at increased risk of developing non-melanoma skin cancer (NMSC) (JEADV Apr. 2016; 30(S3):1–51). The report was produced by a group of leading dermatologists, members of the European Academy of Dermatology and Venereology (EADV) and other experts from around Europe. Data in the report showed that

Link between 'butterfly skin' and squamous cell carcinoma identified

Derm City

Mar 18, 2016
2 min

Link between 'butterfly skin' and squamous cell carcinoma identified

Cells of a cutaneous squamous cell carcinoma (green) that invade the skin. Photo by: Dr. Venugopal Rao Mittapalli, courtesy of the University of Freiburg Researchers from the University of Freiburg in Germany have identified the connection between the genetic skin condition recessive dystrophic epidermolysis bullosa (RDEB) – often called butterfly skin – and the rapidly progressing cutaneous squamous cell carcinomas (SCCs) that 90 per cent of RDEB patients develop, as well as

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Call for entries: 2nd Annual short essay competition for Canadian dermatology residents

it's where dermatology lives

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