Tuesday 09 June, 2015 From 13:30 to 16:30 Location: West Ballroom BCD
SY06 - Pathogenesis of Psoriasis - What's Clinically Relevant? [SY06-05]
Unravelling the environmental component of psoriasis: stimuli transmitted by the Aryl hydrocarbon receptor (AhR) dampen the severity of psoriatic inflammation
Paola Di Meglio
The Francis Crick Institute, London, United Kingdom
In contrast to the fast-growing list of psoriasis susceptibility genes, the environmental factors involved in disease pathogenesis are still ill-defined on a mechanistic base.
The Aryl hydrocarbon receptor (AhR) is a transcription factor and environmental sensor activated by tryptophan metabolites with a protective role in psoriasis, acting as anti-inflammatory brake delivered by non-immune cells to constrain chronic skin inflammation.
Modulation of the AhR pathway might represent a novel therapeutic approach for the treatment of inflammatory skin diseases
Tuesday 09 June, 2015 From 08:00 to 10:00 Location: East 11-12 CME Credits: 2.0
WS02 - Cosmetic Dermatology for the General Dermatologist
[WS02-02] Face peeling formulation and efficacy
Zoe Diana Draelos, Dermatology Consulting Services, High Point, United States
Face peels can be divided into superficial (Glycolic acid, Salicylic acid) and deep (Trichloroacetic acid) based on the acid penetration into the skin.
Glycolic acid peels are water soluble, requiring neutralization, while salicylic acid peels are oil soluble and self neutralizing.
Jessner's peel is a combination peel solution that can be used as a prepeel for a trichloroacetic acid peel to achieve penetration enhancement.
Tricholoracetic acid peels are best used for improving dyspigmentation while superficial peels are better suited to achieve aggressive exfoliation.
Tuesday 09 June, 2015 From 14:30 to 16:30 Location: East 16 CME Credits: 2.0
WS16 - Community Dermatology
[WS16-04] Working with other Neglected Disease Groups: increasing global traction for dermatology
Roderick Hay, International Foundation for Dermatology, London, United Kingdom
It is important to enlarge the definition of neglected diseases to include those affecting the skin by WHO and other organisations
Skin abnormality is the presenting feature of many of the major neglected tropical diseases from leprosy to onchocerciasis.
Teaching the simple diagnostic clues provided by these skin signs will improve case detection - suitable for on line or hard copy access.
Forming alliances to adopt a common approach to disease management including skin involvement will simplify treatment eg a unified management protocol for the chronically swollen limb or ulcer management.