“We had a cure rate of 96% in patients with squamous cell carcinoma and 98% in patients with basal cell carcinoma, and cosmetic outlook was excellent in 90% of cases,” Dr. Narayana said. “This is a great treatment option compared to surgery.”
“We compared the genetic information of patients treated for BCCs and SCCs to that from 600,000 people without these cancers—which allowed us to identify which genes were different between the two groups,” said the study's senior author, associate professor Stuart MacGregor,
In future studies, the researchers will replicate the trial in sample populations with non-European heritage. They are also exploring alternative techniques of calculating genetic risk score and measuring sun exposure, with the goal of developing risk estimates accurate enough to be used by clinicians and patients.
"We discovered that people who develop six or more basal cell carcinomas during a 10-year period are about three times more likely than the general population to develop other, unrelated cancers,” said senior author Dr. Kavita Sarin."
First, two doses of the 9-valent HPV vaccine were administered into the patient’s arm, six weeks apart. A few weeks later, Dr. Nichols directly injected several, but not all, of the patient’s tumours. The direct injections were given four times over a span of 11 months.
Using the generic skin cream fluorouracil 5% (5-FU) for two to four weeks may reduce the risk of a squamous cell carcinoma (SCC) needing surgery by 75%. A single course of 5-FU reduced surgery for SCC for up to one year. The results come from a study published online in the journal JAMA Dermatology (Jan. 3, 2018) which involved military veterans at high risk for keratinocyte carcinoma. A total of 932 veteran...
While there is a common perception that skin pigmentation is protective against skin cancer, even individuals with the most pigmented skin can still develop these conditions, said Edmonton-based dermatologist Dr. Jaggi Rao. The incidence and relative risk of specific sub-types and their presentations differ in different ethnic groups from those of Caucasians, however, he said.
A report from the Mayo Clinic states that incidence rates for basal cell carcinomas (BCCs) and cutaneous squamous cell carcinomas (cSCCs)–particularly cSCCs—are rising and the increase is seen disproportionately in women.
The paper, published online in Mayo Clinic Proceedings (May 15, 2017), was a review of the medical records of a population-based cohort diagnosed with non-melanoma skin cancer between Jan. 2...
Findings from a five-year trial of 5% imiquimod cream for treating superficial and nodular basal cell carcinomas show sustained benefits for those lesions that respond to the cream early, though surgery remains a superior intervention, according to a paper published online ahead of print in Journal of Investigative Dermatology (Dec. 5, 2016).
This research was an extension of an earlier three-year follow-up s...