Data from an online survey of vitiligo patients suggests that, contrary to some case reports, the development of vitiligo may not be a potential side-effect of isotretinoin treatment. The findings suggest instead that there may be some protection against developing vitiligo from the treatment.
A study conducted by researchers at Brigham and Women's Hospital shows that while the number of pregnancies has decreased, pregnancies among women taking isotretinoin have continued even after the implementation of iPLEDGE.
Isotretinoin also reduced the overall number of Propionibacterium bacteria, while it simultaneously increased the diversity of the individual types of the bacteria. Thirty-eight per cent of isotretinoin-treated patients did not show this beneficial pattern in the Propionibacterium communities. This percentage is similar to the proportion of isotretinoin-treated patients in other studies who needed additional...
A project to sequence the genes of a small number of patients with ichthyoses has identified a set of mutations in the KDSR gene which may be responsible for many cases of the debilitating skin conditions. In two patients, their icthyoses were successfully treated by targeting a mutation-related protein deficiency with a common acne medication.