“Our initial finding that skin thickening in psoriasis is due to build-up of dysregulated stem cells and their progeny are exciting because it represents a new way of thinking about an old and significant skin disease.”
“We had a cure rate of 96% in patients with squamous cell carcinoma and 98% in patients with basal cell carcinoma, and cosmetic outlook was excellent in 90% of cases,” Dr. Narayana said. “This is a great treatment option compared to surgery.”
". . . both dermcidin and the cytokine regulator interleukin (IL)‐37 were both significantly downregulated in the HS specimens.
“These findings suggest regulators of the innate immune response and particularly antimicrobial peptide production may play a role in HS pathogenesis,” Dr. Victoria Shanmugam said.
In the press release, Professor Ågren said: “The most frequent response we had from participants was: ‘where can I buy this fantastic product?.’ Even though it contained no fragrance like conventional deodorants, the participants could identify that it had neutralized any bad odour under the arm where it was applied."
Dr. Michael Marks, an assistant professor at the London School of Health & Tropical Hygiene, U.K., said in a press release: “We know that treating individual cases of scabies is not effective, however, treatment of entire communities has been shown in small community-based trials to substantially reduce cases. Our study demonstrates this can be an effective approach when delivered at a larger scale.”
“When human melanoma cell lines were evaluated for growth effects using the chemical inhibitor of p300 HAT, the cell lines that were most sensitive to drug treatment were those that expressed high levels of oMITF, suggesting that MITF expression levels can predict melanoma sensitivity to such therapies,” said Dr. Rhoda Alani.
The Organizing Committee of the 4th Annual Symposium on Hidradenitis Suppurativa Advances (SHSA) has issued a call for abstracts to be included in the symposium as either oral or poster presentations. The deadline for submission is Friday, July 5, and abstracts must be submitted online to www.shsaabstracts.com. Mailed or emailed abstracts will not be accepted.
“Until recently, the scientific community didn’t believe that skin could contribute to systemic inflammation and disease. But in the last five years, studies of psoriasis and dermatitis have shown that skin inflammation from these diseases likely increases the risk of heart disease,” said study lead author Dr. Theodora Mauro
“What makes this trial even more ground-breaking is that the children in the home group were never even admitted to hospital,” said co-senior author Penelope Bryant, PhD. Dr. Bryant is an associate professor and head of the RCH Hospital-in-the-Home program.